Treatment of heart failure was the biggest winner over the past two years. Two successful studies with SGLT2 inhibitors (DAPA-HF and EMPEROR-HF). Another successful study with SGLT1&2 inhibitors. Stimulation of sGC with Verciguat gave some moderate positive result.
Omecamtiv a myosin activator was the first inotropic agent to be safe and beneficial. we learnt also that IV iron therapy is another helpful method.
I am waiting eagerly for the new version of the guidelines to implement the concept of polypharmacy for heat failure treatment.
For me it doesn't look a polypharmacy plan, it looks like we will be prescribing a large meal of medications.
Attached is a detailed summary of the recent updates in heart failure management.
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